VU 0361737 | Tocris Bioscience 3707 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

VU 0361737

catalog :

3707

quantity :

10 mg (also 50 mg)

price :

110 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Jones C, Engers D, Thompson A, Field J, Blobaum A, Lindsley S, et al. Discovery, synthesis, and structure-activity relationship development of a series of N-4-(2,5-dioxopyrrolidin-1-yl)phenylpicolinamides (VU0400195, ML182): characterization of a novel positive allosteric modulator of the metabotropic glutamate recepto. J Med Chem. 2011;54:7639-47 pubmed publisher

product information

brand :

Tocris

master code :

3707

SKU :

3707/10

product name :

VU 0361737

description :

Selective positive allosteric modulator of mGlu4 receptors

target :

Group III mGluR Modulators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

262.69

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective positive allosteric modulator at mGlu4 receptors (EC50 values are 240 and 110 nM at human and rat receptors respectively). Inactive at mGlu1, mGlu2, mGlu3, mGlu6 and mGlu7 receptors and displays weak activity at mGlu5 and mGlu8 receptors. Brain penetrant.

catalog number base :

3707

product keywords :

Selective positive allosteric modulators mGlu4 mGluR4 group III metabotropic glutamate receptors VU0361737 PAM Glutamate (Metabotropic) Group III Receptors 3707,

extended description :

Selective positive allosteric modulator of mGlu4 receptors

chemical name text :

N-(4-Chloro-3-methoxyphenyl)-2-pyridinecarboxamide

formula :

C 13 H 11 ClN 2 O 2

formula text :

C13H11ClN2O2

cas num :

1161205-04-4

2020 USD :

122

2021 USD :

110 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage