RF 9 | Tocris Bioscience 3672/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

RF 9

catalog :

3672/1

quantity :

1 mg

price :

134 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Lee D, Andreev A, Truong T, Chen A, Hill A, Oikonomou G, et al. Genetic and neuronal regulation of sleep by neuropeptide VF. elife. 2017;6: pubmed publisher
Alsaqati M, Latif M, Chan S, Ralevic V. Novel vasocontractile role of the P2Y?? receptor: characterization of its signalling in porcine isolated pancreatic arteries. Br J Pharmacol. 2014;171:701-13 pubmed publisher

product information

brand :

Tocris

master code :

3672

SKU :

3672/1

rank :

0.061

product name :

RF 9

description :

Selective NPFF1 and NPFF2 antagonist

target :

Neuropeptide FF/AF Receptor Antagonists

category :

Small Molecules

sizes available :

1 mg

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

RF 9 is a selective NPFF receptor antagonist (Ki values are 58 and 75 nM at hNPFF1 and hNPFF2 receptors respectively). Displays selectivity over several related receptors including NPY Y1 GPR10, GPR54, GPR103 and the opioid receptors. Blocks NPFF-induced hypothermia and increases in atrial blood pressure and heart rate, and prevents opioid-induced tolerance associated with hyperalgesia in vivo .

extended description :

Selective NPFF1 and NPFF2 antagonist

formula :

C 26 H 38 N 6 O 3

formula text :

C26H38N6O3

cas num :

876310-60-0

USD :

134 USD

product details :

Selective NPFF1 and NPFF2 antagonist

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage