product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
SR 3677 dihydrochloride
catalog :
3667/10
quantity :
10 mg (also 50 mg)
price :
315 USD
more info or order :
citations: 2
Reference
Lotz Jenne C, Lüthi U, Ackerknecht S, Lehembre F, Fink T, Stritt M, et al. A high-content EMT screen identifies multiple receptor tyrosine kinase inhibitors with activity on TGFβ receptor. Oncotarget. 2016;7:25983-6002 pubmed publisher
El Sayed F, Camden J, Woods L, Khalafalla M, Petris M, Erb L, et al. P2Y2 nucleotide receptor activation enhances the aggregation and self-organization of dispersed salivary epithelial cells. Am J Physiol Cell Physiol. 2014;307:C83-96 pubmed publisher
product information
brand :
Tocris
master code :
3667
SKU :
3667/10
rank :
0.061
product name :
SR 3677 dihydrochloride
description :
Potent, selective Rho-kinase (ROCK) inhibitor
target :
Rho-kinase Inhibitors
category :
Small Molecules
sizes available :
10 mg (also 50 mg)
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
SR 3677 dihydrochloride is a potent and selective Rho-kinase inhibitor (IC50 values are 3 and 56 nM for ROCK-II and ROCK-I respectively).
extended description :
Potent, selective Rho-kinase (ROCK) inhibitor
chemical name text :
N-[2-[2-(Dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl-2,3-dihydro-1,4-benzodioxin-2-carboxamide dihydrochloride
formula :
C 22 H 24 N 4 O 4 .2HCl
formula text :
C22H24N4O4.2HCl
cas num :
1781628-88-3
USD :
315 USD
product details :
Potent, selective Rho-kinase (ROCK) inhibitor
storage :
Store the unopened product at room temperature. Do not use past expiration date.
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK