3667/10 | Tocris Bioscience 3667/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

3667/10

catalog :

3667/10

quantity :

10 mg (also 50 mg)

price :

342 USD

citations: 3

Reference
Diep D, Hong K, Khun T, Zheng M, Ul Haq A, Jun H, et al. Anti-adipogenic effects of KD025 (SLx-2119), a ROCK2-specific inhibitor, in 3T3-L1 cells. Sci Rep. 2018;8:2477 pubmed publisher
Lotz Jenne C, Lüthi U, Ackerknecht S, Lehembre F, Fink T, Stritt M, et al. A high-content EMT screen identifies multiple receptor tyrosine kinase inhibitors with activity on TGFβ receptor. Oncotarget. 2016;7:25983-6002 pubmed publisher
El Sayed F, Camden J, Woods L, Khalafalla M, Petris M, Erb L, et al. P2Y2 nucleotide receptor activation enhances the aggregation and self-organization of dispersed salivary epithelial cells. Am J Physiol Cell Physiol. 2014;307:C83-96 pubmed publisher

product information

master code :

3667

SKU :

3667/10

product name :

SR 3677 dihydrochloride

unit size :

10 mg (also 50 mg)

description :

Potent, selective Rho-kinase (ROCK) inhibitor

target :

Rho-kinase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

481.37

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SR 3677 dihydrochloride is a potent and selective Rho-kinase inhibitor (IC50 values are 3 and 56 nM for ROCK-II and ROCK-I respectively).

top caption :

Potent, selective Rho-kinase (ROCK) inhibitor

extended description :

Potent, selective Rho-kinase (ROCK) inhibitor

chemical name text :

N-[2-[2-(Dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl-2,3-dihydro-1,4-benzodioxin-2-carboxamide dihydrochloride

formula :

C22H24N4O4.2HCl

formula text :

C22H24N4O4.2HCl

cas num :

1781628-88-3

USD :

342 USD

product details :

Potent, selective Rho-kinase (ROCK) inhibitor

storage :

Desiccate at RT