GSK 4112 | Tocris Bioscience 3663 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

GSK 4112

catalog :

3663

quantity :

10 mg (also 50 mg)

price :

169 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Chandra V, Bhagyaraj E, Nanduri R, Ahuja N, Gupta P. NR1D1 ameliorates Mycobacterium tuberculosis clearance through regulation of autophagy. Autophagy. 2015;11:1987-1997 pubmed publisher

product information

brand :

Tocris

master code :

3663

SKU :

3663/10

product name :

GSK 4112

description :

Selective Rev-Erb agonist

target :

Nuclear Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

396.89

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective Rev-Erb agonist (EC50 = 250 nM). Enhances recruitment of nuclear receptor co-repressor (NCoR) peptide to Rev-Erb ; causes acute suppression of Bmal1 gene transcription. Induces phase shifts in the circadian clock.

catalog number base :

3663

product keywords :

GSK4112 REV-ERBA REV-ERB REV-ERBalpha agonists circadian rhythms SR6452 SR 6452 Rev-Erb Receptors 3663,

extended description :

Selective Rev-Erb agonist

chemical name text :

1,1-Dimethylethyl-N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate

formula :

C 18 H 21 ClN 2 O 4 S

formula text :

C18H21ClN2O4S

cas num :

1216744-19-2

2020 USD :

164

2021 USD :

169 USD

alt names :

SR 6452

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage