GSK 4112 | Tocris Bioscience 3663/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

GSK 4112

catalog :

3663/10

quantity :

10 mg (also 50 mg)

price :

196 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Chandra V, Bhagyaraj E, Nanduri R, Ahuja N, Gupta P. NR1D1 ameliorates Mycobacterium tuberculosis clearance through regulation of autophagy. Autophagy. 2015;11:1987-1997 pubmed publisher

product information

brand :

Tocris

master code :

3663

SKU :

3663/10

rank :

0.061

product name :

GSK 4112

description :

Selective Rev-Erb agonist

target :

Nuclear Receptor Agonists

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

GSK 4112 is a selective Rev-Erb agonist (EC50 = 250 nM). Enhances recruitment of nuclear receptor co-repressor (NCoR) peptide to Rev-Erb ; causes acute suppression of Bmal1 gene transcription. Induces phase shifts in the circadian clock.

extended description :

Selective Rev-Erb agonist

chemical name text :

1,1-Dimethylethyl-N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate

formula :

C 18 H 21 ClN 2 O 4 S

formula text :

C18H21ClN2O4S

cas num :

1216744-19-2

USD :

196 USD

product details :

Selective Rev-Erb agonist

alt names :

SR 6452

storage :

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage