Sal 003 | Tocris Bioscience 3657 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Sal 003

catalog :

3657

quantity :

10 mg (also 50 mg)

price :

182 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Krokowski D, Guan B, Wu J, Zheng Y, Pattabiraman P, Jobava R, et al. GADD34 Function in Protein Trafficking Promotes Adaptation to Hyperosmotic Stress in Human Corneal Cells. Cell Rep. 2017;21:2895-2910 pubmed publisher
Devi L, Ohno M. Phospho-eIF2? level is important for determining abilities of BACE1 reduction to rescue cholinergic neurodegeneration and memory defects in 5XFAD mice. PLoS ONE. 2010;5:e12974 pubmed publisher

product information

brand :

Tocris

master code :

3657

SKU :

3657/10

product name :

Sal 003

description :

Cell-permeable inhibitor of eIF2 dephosphorylation

target :

Protein Ser/Thr Phosphatase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

463.21

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Cell-permeable inhibitor of cellular phosphatase complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit (eIF2 ). Analog of salubrinal (Cat. No. 2347) with improved aqueous solubility. Shown to prevent the induction of hippocampal long-term potentiation (LTP) and memory formation (LTM) in mice.

catalog number base :

3657

product keywords :

Cell permeable inhibitors cellular phosphatases complexes dephosphorylates eukaryotic translation initiation factor 2 subunit α eIF2 eIF2a eIF2alpha Sal003 inhibits Protein Ser/Thr Phosphatases Protein-synthesizing GTPases 3657,

extended description :

Cell-permeable inhibitor of eIF2 dephosphorylation

chemical name text :

3--Phenyl-N-(2,2,2-trichloro-1-((((4-chlorophenyl)amino)carbonothioyl)amino)ethyl)acrylamide

formula :

C 18 H 15 Cl 4 N 3 OS

formula text :

C18H15Cl4N3OS

cas num :

1164470-53-4

2020 USD :

175

2021 USD :

182 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage