Sal 003 | Tocris Bioscience 3657/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Sal 003

catalog :

3657/10

quantity :

10 mg (also 50 mg)

price :

212 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Krokowski D, Guan B, Wu J, Zheng Y, Pattabiraman P, Jobava R, et al. GADD34 Function in Protein Trafficking Promotes Adaptation to Hyperosmotic Stress in Human Corneal Cells. Cell Rep. 2017;21:2895-2910 pubmed publisher
Devi L, Ohno M. Phospho-eIF2? level is important for determining abilities of BACE1 reduction to rescue cholinergic neurodegeneration and memory defects in 5XFAD mice. PLoS ONE. 2010;5:e12974 pubmed publisher

product information

brand :

Tocris

master code :

3657

SKU :

3657/10

rank :

0.061

product name :

Sal 003

description :

Cell-permeable inhibitor of eIF2 dephosphorylation

target :

Protein Ser/Thr Phosphatase Inhibitors

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Sal 003 is a cell-permeable inhibitor of cellular phosphatase complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit (eIF2 ). Analog of salubrinal (Cat. No. 2347) with improved aqueous solubility. Shown to prevent the induction of hippocampal long-term potentiation (LTP) and memory formation (LTM) in mice.

extended description :

Cell-permeable inhibitor of eIF2 dephosphorylation

chemical name text :

3--Phenyl-N-(2,2,2-trichloro-1-((((4-chlorophenyl)amino)carbonothioyl)amino)ethyl)acrylamide

formula :

C 18 H 15 Cl 4 N 3 OS

formula text :

C18H15Cl4N3OS

cas num :

1164470-53-4

USD :

212 USD

product details :

Cell-permeable inhibitor of eIF2 dephosphorylation

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage