SB 328437 | Tocris Bioscience 3650 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SB 328437

catalog :

3650

quantity :

10 mg

price :

195 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

3650

SKU :

3650/10

product name :

SB 328437

description :

Potent and selective CCR3 antagonist

target :

Chemokine Receptor Antagonists

category :

Small Molecules

unit size :

10 mg

purity :

99%

observed molecular weight :

378.38

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective CCR3 antagonist (IC50 = 4 nM). Displays 2500-fold selectivity over C5aR, LTD4, CCR7, CXCR1 and CXCR2 receptors. Inhibits eotaxin-, eotaxin-2- and MCP-4-induced Ca2+ mobilization (IC50 values are 38, 35 and 20 nM respectively) and inhibits eotaxin-, eotaxin-2- and MCP-4-induced eosinophil chemotaxis with similar potencies.

catalog number base :

3650

product keywords :

SB328437 Potent selective CCR3 antagonists chemokine receptors Rantes Chemokine CC Receptors 3650,

extended description :

Potent and selective CCR3 antagonist

chemical name text :

N-(1-Naphthalenylcarbonyl)-4-nitro-L-phenylalanine methyl ester

formula :

C 21 H 18 N 2 O 5

formula text :

C21H18N2O5

cas num :

247580-43-4

2020 USD :

187

2021 USD :

195 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage