CP 122721 hydrochloride | Tocris Bioscience 3649 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CP 122721 hydrochloride

catalog :

3649

quantity :

25 mg

price :

479 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

3649

SKU :

3649/25

product name :

CP 122721 hydrochloride

description :

High affinity NK1 antagonist

target :

NK1 Receptor Antagonists

category :

Small Molecules

unit size :

25 mg

purity :

98%

observed molecular weight :

453.33

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

High affinity NK1 antagonist (pIC50 = 9.8). Suppresses recruitment of immunocytes in respiratory syncytial virus (RSV)-infected rats after capsaicin stimulation. Also blocks substance P-induced excitation of locus ceruleus cells in guinea pig brain slices (IC50 = 7 nM). Exhibits anxiolytic and antidepressant-like effects. Active in vivo .

catalog number base :

3649

product keywords :

CP122721 hydrochloride 145742-28-5 K1 antagonists antagonism tachykinin receptors neurokinin 1 NK1 substance P SP depression emesis inflammatory diseases asthma irritable bowel syndrome antiemetics IBS NK1 Receptor 3649, Neurokinin NK1

extended description :

High affinity NK1 antagonist

chemical name text :

(2S,3S)-N-[[2-Methoxy-5-(trifluoromethoxy)phenyl]methyl]-2-phenyl-3-piperidinamine dihydrochloride

formula :

C 20 H 23 F 3 N 2 O 2 .2HCl

formula text :

C20H23F3N2O2.2HCl

cas num :

145877-52-7

2020 USD :

465

2021 USD :

479 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage