Src I1 | Tocris Bioscience 3642/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Src I1

catalog :

3642/10

quantity :

10 mg (also 50 mg)

price :

192 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Zhang Z, La Placa D, Nguyen T, Kujawski M, Le K, Li L, et al. CEACAM1 regulates the IL-6 mediated fever response to LPS through the RP105 receptor in murine monocytes. BMC Immunol. 2019;20:7 pubmed publisher
Leung W, Vong Q, Lin W, Bouck D, Wendt S, Sullivan E, et al. PRL-3 mediates the protein maturation of ULBP2 by regulating the tyrosine phosphorylation of HSP60. J Immunol. 2015;194:2930-41 pubmed publisher

product information

brand :

Tocris

master code :

3642

SKU :

3642/10

rank :

0.061

product name :

Src I1

description :

Dual site Src kinase inhibitor

target :

Src Family Kinase Inhibitors

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Src I1 is a potent, competitive dual site (ATP- and peptide-binding) Src kinase inhibitor (IC50 values are 44 and 88 nM for Src and Lck respectively). Inhibits VEGFR2 and c-fms at higher concentrations (IC50 values are 0.32 and 30 M respectively). Can be used in parallel with PP 1 (Cat. No. 1397) and PP 2 (Cat. No. 1407) to inhibit Src family kinases.

extended description :

Dual site Src kinase inhibitor

chemical name text :

6,7-Dimethoxy-N-(4-phenoxyphenyl)-4-quinazolinamine

formula :

C 22 H 19 N 3 O 3

formula text :

C22H19N3O3

cas num :

179248-59-0

USD :

192 USD

product details :

Dual site Src kinase inhibitor

storage :

Store the unopened product at room temperature. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage