product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Adenosine 5'-(a,b-methylene)diphosphate sodium salt
catalog :
3633
quantity :
10 mg
price :
227 USD
more info or order :
citations: 2
Reference
Wu J, Li Y, Yang L, Hu Y, Hu X, Tang T, et al. Borneol and Α-asarone as adjuvant agents for improving blood-brain barrier permeability of puerarin and tetramethylpyrazine by activating adenosine receptors. Drug Deliv. 2018;25:1858-1864 pubmed publisher
Caiazzo E, Maione F, Morello S, Lapucci A, Paccosi S, Steckel B, et al. Adenosine signalling mediates the anti-inflammatory effects of the COX-2 inhibitor nimesulide. Biochem Pharmacol. 2016;112:72-81 pubmed publisher
product information
brand :
Tocris
master code :
3633
SKU :
3633/10
product name :
Adenosine 5'-(a,b-methylene)diphosphate sodium salt
description :
Ecto-5 -nucleotidase (CD73) inhibitor
target :
NTPDase Inhibitors
category :
Small Molecules
unit size :
10 mg
purity :
98%
observed molecular weight :
447.21
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Ecto-5 -nucleotidase/CD73 inhibitor. Blocks ecto-5 -nucleotidase-mediated adenosine production by preventing the conversion of AMP to adenosine. Reverses the doxorubicin-resistance in ecto-5 -nucleotidase-positive MDR cells (MCF7/A6 and L1210/A). Also increases rhodamine uptake and inhibits rhodamine efflux from ecto-5 -nucleotidase-positive MDR cells. Vasoconstrictor.
catalog number base :
3633
product keywords :
[3768-14-7] MS multiple sclerosis Ecto-5 -nucleotidase/ CD73 inhibitors inhibits adenosine doxorubicin-resistance vasoconstrictor NT5E eN eNT 5' nucleotidase ecto-5 -NT 5-(a,b-methylene)diphosphate AMPCP APCP NTPDase 3633,
extended description :
Ecto-5 -nucleotidase (CD73) inhibitor
chemical name text :
, -Methyleneadenosine 5 -diphosphate monosodium salt
formula :
C 11 H 16 N 5 NaO 9 P 2
formula text :
C11H16N5NaO9P2
cas num :
89016-30-8
2020 USD :
216
2021 USD :
227 USD
alt names :
AMPCP, APCP
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK