UBP 310 | Tocris Bioscience 3621 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

UBP 310

catalog :

3621

quantity :

10 mg (also 50 mg)

price :

184 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Crook J, Packer O, Dacey D. A synaptic signature for ON- and OFF-center parasol ganglion cells of the primate retina. Vis Neurosci. 2014;31:57-84 pubmed publisher
Buldyrev I, Puthussery T, Taylor W. Synaptic pathways that shape the excitatory drive in an OFF retinal ganglion cell. J Neurophysiol. 2012;107:1795-807 pubmed publisher

product information

brand :

Tocris

master code :

3621

SKU :

3621/10

product name :

UBP 310

description :

GluK1-selective kainate antagonist

target :

Kainate Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

353.35

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

GluK1 (formerly GLUK5) kainate receptor antagonist (IC50 = 130 nM); also blocks recombinant homomeric GluK3 (forrmerly GLUK7) receptors. Displays 12,700-fold selectivity for GluK1 (formerly GLUK5) over GluK2 (formerly GLUK6). Exhibits no activity at mGlu group I or NMDA receptors at concentrations of up to 10 M. Apparent KD value is 18 4 nM for depression of kainate responses on the dorsal root. . Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions .

catalog number base :

3621

product keywords :

UBP310 kainate receptors antagonists GLUK5 iGlu ionotropic glutamate GluK1 Kainate Receptors 3621,

extended description :

GluK1-selective kainate antagonist

chemical name text :

(S)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxy-thiophene-3-yl-methyl)-5-methylpyrimidine-2,4-dione

formula :

C 14 H 15 N 3 O 6 S

formula text :

C14H15N3O6S

cas num :

902464-46-4

2020 USD :

176

2021 USD :

184 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage