SANT-2 | Tocris Bioscience 3617 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SANT-2

catalog :

3617

quantity :

10 mg (also 50 mg)

price :

201 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Strating J, van der Linden L, Albulescu L, Bigay J, Arita M, Delang L, et al. Itraconazole inhibits enterovirus replication by targeting the oxysterol-binding protein. Cell Rep. 2015;10:600-15 pubmed publisher

product information

brand :

Tocris

master code :

3617

SKU :

3617/10

product name :

SANT-2

description :

Inhibitor of Hedgehog (Hh) signaling; antagonizes smoothened activity

target :

Hedgehog Signaling Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

479.96

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inhibitor of Sonic hedgehog (Shh) signaling; antagonizes smoothened receptor activity (KD = 12 nM). Displays allosteric binding characteristics similar to SANT-1 (Cat. No. 1974). Displaces smo-[3H]SAG-1.3 and -[3H]Cyclopamine binding (Ki values are 7.8 nM and 8.4 nM respectively).

catalog number base :

3617

product keywords :

inhibitors inhibits Hedgehog Hh signaling signalling antagonizes antagonises smoothened smo receptors antagonist Hedgehog Signaling Smoothened Receptors 3617,

extended description :

Inhibitor of Hedgehog (Hh) signaling; antagonizes smoothened activity

chemical name text :

N-[3-(1H-Benzimidazol-2-yl)-4-chlorophenyl]-3,4,5-triethoxybenzamide

formula :

C 26 H 26 ClN 3 O 4

formula text :

C26H26ClN3O4

cas num :

329196-48-7

2020 USD :

201

2021 USD :

201 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage