3610/10 | Tocris Bioscience 3610/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

3610/10

catalog :

3610/10

quantity :

10 mg (also 50 mg)

price :

319 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Goonesekere N, Wang X, Ludwig L, Guda C. A meta analysis of pancreatic microarray datasets yields new targets as cancer genes and biomarkers. PLoS ONE. 2014;9:e93046 pubmed publisher

product information

master code :

3610

SKU :

3610/10

product name :

(R)-DRF053 dihydrochloride

unit size :

10 mg (also 50 mg)

description :

Potent CK1 inhibitor; also inhibits cyclin-dependent kinases

target :

Casein Kinase 1 Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

490.43

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

( R )-DRF053 dihydrochloride is a potent casein kinase 1 (CK1) inhibitor (IC50 = 14 nM). Also an ATP-competitive cyclin-dependent kinase (cdk) inhibitor (IC50 values are 0.093 - 0.29, 0.21 and 0.82 M for cdk2, cdk5 and cdk7, respectively). Shown to inhibit amyloid- production in N2A-APP695 cells.

top caption :

Potent CK1 inhibitor; also inhibits cyclin-dependent kinases

extended description :

Potent CK1 inhibitor; also inhibits cyclin-dependent kinases

chemical name text :

2-[[9-(1-Methylethyl)-6-[[3-(2-pyridinyl)phenyl]amino]-9H-purin-2-yl]amino]-1-butanol dihydrochloride

formula :

C23H27N7O.2HCl

formula text :

C23H27N7O.2HCl

cas num :

1241675-76-2

USD :

319 USD

product details :

Potent CK1 inhibitor; also inhibits cyclin-dependent kinases

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage