3607/10 | Tocris Bioscience 3607/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

3607/10

catalog :

3607/10

quantity :

10 mg (also 50 mg)

price :

239 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
van Gent M, van der Reijden T, Lennard P, de Visser A, Schonkeren Ravensbergen B, Dolezal N, et al. Synergism between the Synthetic Antibacterial and Antibiofilm Peptide (SAAP)-148 and Halicin. Antibiotics (Basel). 2022;11: pubmed publisher
Jang S, Yu L, Abdelmegeed M, Gao Y, Banerjee A, Song B. Critical role of c-jun N-terminal protein kinase in promoting mitochondrial dysfunction and acute liver injury. Redox Biol. 2015;6:552-564 pubmed publisher
Lo H, Lai T, Li C, Wu W. TNF-? induces CXCL1 chemokine expression and release in human vascular endothelial cells in vitro via two distinct signaling pathways. Acta Pharmacol Sin. 2014;35:339-50 pubmed publisher
Shaw J, Lloyd P. Post-transcriptional regulation of placenta growth factor mRNA by hydrogen peroxide. Microvasc Res. 2012;84:155-60 pubmed publisher

product information

master code :

3607

SKU :

3607/10

product name :

SU 3327

unit size :

10 mg (also 50 mg)

description :

Selective JNK inhibitor

target :

JNK/c-jun Inhibitors

category :

Small Molecules

purity :

99%

observed molecular weight :

261.3

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SU 3327 is a selective inhibitor of c-Jun N-terminal kinase (JNK) (IC50 = 0.7 M). Inhibits the protein-protein interaction between JNK and JIP (IC50 = 239 nM). Displays selectivity over p38 MAPK and Akt. Restores insulin sensitivity in a mouse model of type-2 diabetes. Displays antibiotic activity against a range of bacteria including S.aureus , A.baumanni , C.difficile and M.tuberculosis .

top caption :

Selective JNK inhibitor

extended description :

Selective JNK inhibitor

chemical name text :

5-[(5-Nitro-2-thiazolyl)thio]-1,3,4thiadiazol-2-amine

formula :

C5H3N5O2S3

formula text :

C5H3N5O2S3

cas num :

40045-50-9

USD :

239 USD

product details :

Selective JNK inhibitor

alt names :

Halicin

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage