BAG 956 | Tocris Bioscience 3606 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BAG 956

catalog :

3606

quantity :

10 mg (also 50 mg)

price :

263 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

3606

SKU :

3606/10

product name :

BAG 956

description :

Dual PI 3-kinase and PDPK1 (PDK1) inhibitor

target :

PI 3-Kinase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

427.5

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Dual PDPK1 (PDK1) and class I PI 3-K inhibitor (IC50 values are 245, 56, 446, 35 and 117 nM for PDPK1 and PI 3-K p110 - , - , - , and - respectively). Inhibits cellular AKT phosphorylation at Thr308. Blocks cell proliferation, causing arrest in G1 phase of the cell cycle. Slows tumor progression in mouse xenograft models.

catalog number base :

3606

product keywords :

Dual inhibitors PDK PDK1 PI3K p110 inhibits PI 3-kinases Signaling Signalling Phosphoinositide Kinases PIP2 Inositol Lipids cAMP 3-phosphoinositide dependent protein kinase-1 BAG956 PDPK1 PI 3-Kinase Inositol Lipids Phosphoinositide-dependent Kinase 1 PDK1 3606,

extended description :

Dual PI 3-kinase and PDPK1 (PDK1) inhibitor

chemical name text :

, ,-Dimethyl-4-[2-methyl-8-[2-(3-pyridinyl)ethynyl]-1H-imidazo[4,5-c]quinolin-1-yl]-benzeneacetonitrile

formula :

C 28 H 21 N 5

formula text :

C28H21N5

cas num :

853910-02-8

2020 USD :

263

2021 USD :

263 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage