BAG 956 | Tocris Bioscience 3606/10 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BAG 956

catalog :

3606/10

quantity :

10 mg (also 50 mg)

price :

331 USD

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

3606

SKU :

3606/10

product name :

BAG 956

description :

Dual PI 3-kinase and PDPK1 (PDK1) inhibitor

target :

PI 3-Kinase Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

427.5

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

BAG 956 is a dual PDPK1 (PDK1) and class I PI 3-K inhibitor (IC50 values are 245, 56, 446, 35 and 117 nM for PDPK1 and PI 3-K p110 - , - , - , and - respectively). Inhibits cellular AKT phosphorylation at Thr308. Blocks cell proliferation, causing arrest in G1 phase of the cell cycle. Slows tumor progression in mouse xenograft models.

product keywords :

Dual inhibitors PDK PDK1 PI3K p110 inhibits PI 3-kinases Signaling Signalling Phosphoinositide Kinases PIP2 Inositol Lipids cAMP 3-phosphoinositide dependent protein kinase-1 BAG956 PDPK1 PI 3-Kinase Inositol Lipids Phosphoinositide-dependent Kinase 1 PDK1 3606,

extended description :

Dual PI 3-kinase and PDPK1 (PDK1) inhibitor

chemical name text :

, ,-Dimethyl-4-[2-methyl-8-[2-(3-pyridinyl)ethynyl]-1H-imidazo[4,5-c]quinolin-1-yl]-benzeneacetonitrile

formula :

C28H21N5

formula text :

C28H21N5

cas num :

853910-02-8

USD :

327

USD 2025 :

331 USD

product details :

Dual PI 3-kinase and PDPK1 (PDK1) inhibitor