product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
3601/10
catalog :
3601/10
quantity :
10 mg (also 50 mg)
price :
299 USD
more info or order :
citations: 6
Reference |
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Chumanevich A, Wedman P, Oskeritzian C. Sphingosine-1-Phosphate/Sphingosine-1-Phosphate Receptor 2 Axis Can Promote Mouse and Human Primary Mast Cell Angiogenic Potential through Upregulation of Vascular Endothelial Growth Factor-A and Matrix Metalloproteinase-2. Mediators Inflamm. 2016;2016:1503206 pubmed publisher
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Janes K, Little J, Li C, Bryant L, Chen C, Chen Z, et al. The development and maintenance of paclitaxel-induced neuropathic pain require activation of the sphingosine 1-phosphate receptor subtype 1. J Biol Chem. 2014;289:21082-97 pubmed
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product information
master code :
3601
SKU :
3601/10
product name :
CYM 5442 hydrochloride
unit size :
10 mg (also 50 mg)
description :
Selective S1P1 receptor agonist
target :
Sphingosine-1-phosphate Receptor Agonists
category :
Small Molecules
purity :
98%
observed molecular weight :
445.94
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
CYM 5442 hydrochloride is a potent and selective S1P1 agonist in vitro (EC50 = 1.35 nM). Activates S1P1-mediated p42/p44 MAPK phosphorylation in CHO-K1 cells transfected with S1P1. Induces acute lymphopenia in mice. Brain penetrant.
top caption :
Selective S1P1 receptor agonist
extended description :
Selective S1P1 receptor agonist
chemical name text :
2-(4-(5-(3,4-Diethoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl amino) ethanol hydrochloride
formula :
C23H27N3O4.HCl
formula text :
C23H27N3O4.HCl
cas num :
1783987-80-3
USD :
299 USD
product details :
Selective S1P1 receptor agonist
storage :
Store at -20░C
more info or order :
company information

Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
headquarters: UK
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