TAK 165 | Tocris Bioscience 3599 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TAK 165

catalog :

3599

quantity :

10 mg (also 50 mg)

price :

198 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

3599

SKU :

3599/10

product name :

TAK 165

description :

Potent and selective ErbB2 inhibitor

target :

EGF Receptor Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

468.47

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent, irreversible human epithelial growth factor receptor 2 (ErbB2) inhibitor (IC50 = 6 nM) that displays 4000-fold selectivity over EGFR, FGFR, PDGFR, JAK1 and Src. Exhibits potent antiproliferative effects in ErbB2-overexpressing cancer cell lines (IC50 = 5 nM in BT474 breast cancer cells) and significantly inhibits bladder, breast and prostate cancer xenograft growth in vivo .

catalog number base :

3599

product keywords :

Potent selective ErbB2 inhibitors inhibits Epidermal Growth Factor Receptors Her EGFR Receptor Tyrosine Kinases RTKs TAK165 Mubritinib EGFR 3599,

extended description :

Potent and selective ErbB2 inhibitor

chemical name text :

1-[4-[4-[[2-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-4-oxazolyl]methoxy]phenyl]butyl]-1H-1,2,3-triazole

formula :

C 25 H 23 F 3 N 4 O 2

formula text :

C25H23F3N4O2

cas num :

366017-09-6

2020 USD :

194

2021 USD :

198 USD

alt names :

Mubritinib

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage