product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
3586/10
catalog :
3586/10
quantity :
10 mg (also 50 mg)
price :
134 USD
more info or order :
citations: 4
Reference
Burke D, Alvarez V. Serotonin receptors contribute to dopamine depression of lateral inhibition in the nucleus accumbens. Cell Rep. 2022;39:110795 pubmed publisher
Gadgaard C, Jensen A. Functional characterization of 5-HT1A and 5-HT1B serotonin receptor signaling through G-protein-activated inwardly rectifying K+ channels in a fluorescence-based membrane potential assay. Biochem Pharmacol. 2020;175:113870 pubmed publisher
Moldovan Loomis C, Dutzar B, Ojala E, Hendrix L, Karasek C, Scalley Kim M, et al. Pharmacologic Characterization of ALD1910, a Potent Humanized Monoclonal Antibody against the Pituitary Adenylate Cyclase-Activating Peptide. J Pharmacol Exp Ther. 2019;369:26-36 pubmed publisher
Matsui A, Alvarez V. Cocaine Inhibition of Synaptic Transmission in the Ventral Pallidum Is Pathway-Specific and Mediated by Serotonin. Cell Rep. 2018;23:3852-3863 pubmed publisher
product information
master code :
3586
SKU :
3586/10
product name :
Sumatriptan succinate
unit size :
10 mg (also 50 mg)
description :
5-HT1A, 5-HT1B and 5-HT1D agonist
target :
Non-selective 5-HT1 Receptor Agonists
category :
Small Molecules
purity :
99%
observed molecular weight :
413.49
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Sumatriptan succinate is a 5-HT1 receptor agonist (Ki values are 17, 27 and 100 nM at 5-HT1D, 5-HT1B and 5-HT1A receptors respectively). Antimigraine agent.
top caption :
5-HT1A, 5-HT1B and 5-HT1D agonist
extended description :
5-HT1A, 5-HT1B and 5-HT1D agonist
chemical name text :
3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate
formula :
C14H21N3O2S.C4H6O4
formula text :
C14H21N3O2S.C4H6O4
cas num :
103628-48-4
USD :
134 USD
product details :
5-HT1A, 5-HT1B and 5-HT1D agonist
alt names :
GR 43175
storage :
Store at +4░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK