Golgicide A | Tocris Bioscience 3584 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Golgicide A

catalog :

3584

quantity :

10 mg (also 50 mg)

price :

223 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Gomes da Silva L, Jimenez A, Sauvat A, Xie W, Souquere S, Divoux S, et al. Recruitment of LC3 to damaged Golgi apparatus. Cell Death Differ. 2018;: pubmed publisher
Krokowski D, Guan B, Wu J, Zheng Y, Pattabiraman P, Jobava R, et al. GADD34 Function in Protein Trafficking Promotes Adaptation to Hyperosmotic Stress in Human Corneal Cells. Cell Rep. 2017;21:2895-2910 pubmed publisher

product information

brand :

Tocris

master code :

3584

SKU :

3584/10

product name :

Golgicide A

description :

Potent, selective and reversible inhibitor of GBF1 ArfGEF

target :

ARF GTPase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

284.3

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent, specific and reversible inhibitor of Golgi BFA resistance factor 1 (GBF1), an ArfGEF, that decreases Arf1 activation in vivo . Arrests secretion of soluble and membrane-associated proteins at the endoplasmic reticulum-Golgi intermediate compartment. Causes disassembly and dispersal of the Golgi and trans -Golgi network.

catalog number base :

3584

product keywords :

potent specific reversible inhibitors inhibits Golgi BFA resistance factors 1 GBF1 ArfGEF ADP ribosylation factor guanine nucleotide exchange Translocation, Exocytosis & Endocytosis Arf Translocation 3584, ARF, ADP ribosylation factor, GTP ase,

extended description :

Potent, selective and reversible inhibitor of GBF1 ArfGEF

chemical name text :

6,8-Difluoro-4-pyridin-3-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline

formula :

C 17 H 14 F 2 N 2

formula text :

C17H14F2N2

cas num :

1139889-93-2

2020 USD :

216

2021 USD :

223 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage