VU 0155069 | Tocris Bioscience 3575 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

VU 0155069

catalog :

3575

quantity :

10 mg (also 50 mg)

price :

231 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Lu W, Chung C, Chen R, Huang L, Lien L, Chang C, et al. An Antithrombotic Strategy by Targeting Phospholipase D in Human Platelets. J Clin Med. 2018;7: pubmed publisher
Krishnan B, Kayed R, Taglialatela G. Elevated phospholipase D isoform 1 in Alzheimer's disease patients' hippocampus: Relevance to synaptic dysfunction and memory deficits. Alzheimers Dement (N Y). 2018;4:89-102 pubmed publisher
Sulzmaier F, Valmiki M, Nelson D, Caliva M, Geerts D, Matter M, et al. PEA-15 potentiates H-Ras-mediated epithelial cell transformation through phospholipase D. Oncogene. 2012;31:3547-60 pubmed publisher

product information

brand :

Tocris

master code :

3575

SKU :

3575/10

product name :

VU 0155069

description :

Potent and selective PLD1 inhibitor

target :

Phospholipase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

499.43

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective phospholipase D1 (PLD1) inhibitor (IC50 values are 46 and 933 nM for PLD1 and PLD2 respectively). Inhibits migration of human and mouse breast cancer cell lines in transwell assays.

catalog number base :

3575

product keywords :

VU0155069 PLD1 phospholipases D specific inhibitors inhibits potent selective esterases Phospholipases 3575,

extended description :

Potent and selective PLD1 inhibitor

chemical name text :

N-[(1S)-2-[4-(5-Chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]-1-methylethyl-2-naphthalenecarboxamide

formula :

C 26 H 27 ClN 4 O 2 .HCl

formula text :

C26H27ClN4O2.HCl

cas num :

1781834-89-6

2020 USD :

224

2021 USD :

231 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage