VU 0155069 | Tocris Bioscience 3575/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

VU 0155069

catalog :

3575/10

quantity :

10 mg (also 50 mg)

price :

290 USD

citations: 5

Reference
Ivanova D, Imig C, Camacho M, Reinhold A, Guhathakurta D, Montenegro Venegas C, et al. CtBP1-Mediated Membrane Fission Contributes to Effective Recycling of Synaptic Vesicles. Cell Rep. 2020;30:2444-2459.e7 pubmed publisher
Lu W, Chung C, Chen R, Huang L, Lien L, Chang C, et al. An Antithrombotic Strategy by Targeting Phospholipase D in Human Platelets. J Clin Med. 2018;7: pubmed publisher
Krishnan B, Kayed R, Taglialatela G. Elevated phospholipase D isoform 1 in Alzheimer's disease patients' hippocampus: Relevance to synaptic dysfunction and memory deficits. Alzheimers Dement (N Y). 2018;4:89-102 pubmed publisher
Luo L, Li G, Wang Y. PLD1 promotes dendritic spine development by inhibiting ADAM10-mediated N-cadherin cleavage. Sci Rep. 2017;7:6035 pubmed publisher
Sulzmaier F, Valmiki M, Nelson D, Caliva M, Geerts D, Matter M, et al. PEA-15 potentiates H-Ras-mediated epithelial cell transformation through phospholipase D. Oncogene. 2012;31:3547-60 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

3575

SKU :

3575/10

product name :

VU 0155069

description :

Potent and selective PLD1 inhibitor

target :

Phospholipase Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

499.43

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

VU 0155069 is a potent and selective phospholipase D1 (PLD1) inhibitor (IC50 values are 46 and 933 nM for PLD1 and PLD2 respectively). Inhibits migration of human and mouse breast cancer cell lines in transwell assays.

product keywords :

VU0155069 PLD1 phospholipases D specific inhibitors inhibits potent selective esterases Phospholipases 3575,

extended description :

Potent and selective PLD1 inhibitor

chemical name text :

N-[(1S)-2-[4-(5-Chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]-1-methylethyl-2-naphthalenecarboxamide

formula :

C26H27ClN4O2.HCl

formula text :

C26H27ClN4O2.HCl

cas num :

1781834-89-6

USD :

287

USD 2025 :

290 USD

product details :

Potent and selective PLD1 inhibitor