Xanomeline oxalate | Tocris Bioscience 3569 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Xanomeline oxalate

catalog :

3569

quantity :

10 mg (also 50 mg)

price :

195 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Tian M, Xu J, Lei G, Lombroso P, Jackson M, MacDonald J. STEP activation by G?q coupled GPCRs opposes Src regulation of NMDA receptors containing the GluN2A subunit. Sci Rep. 2016;6:36684 pubmed publisher

product information

brand :

Tocris

master code :

3569

SKU :

3569/10

product name :

Xanomeline oxalate

description :

Functionally selective M1 agonist

target :

mAChR M1 Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

371.46

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Functionally selective muscarinic M1 receptor agonist (EC50 values are 0.3, 5, 42, 52 and 92.5 nM at M1, M3, M5, M4 and M2 receptors respectively). Displays a complex pharmacological profile: reversible and wash-resistant binding, resulting in full agonist activity at M1; delayed wash-resistant partial agonist activity at M2; and delayed wash-resistant full agonist activity at M4. Exhibits antipsychotic activity, and improves cognitive deficits and behavioral disturbances in Alzheimer s disease and schizophrenia.

catalog number base :

3569

product keywords :

Functionally selective M1 agonists Muscarinic Receptors Acetylcholine ACh M1 Receptors 3569,

extended description :

Functionally selective M1 agonist

chemical name text :

3-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridine oxalate

formula :

C 14 H 23 N 3 OS.C 2 H 2 O 4

formula text :

C14H23N3OS.C2H2O4

cas num :

141064-23-5

2020 USD :

187

2021 USD :

195 USD

storage :

Desiccate at +4°C

more info or order :

Tocris Bioscience product webpage