Tocris Bioscience

chemical

CRSP-1

3555/100

100µg

205 USD

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3555/100

CRSP-1

[697327-12-1]

100µg

100

µg

205 USD

7-TM Receptors

Peptide Receptors

Calcitonin and Related Receptors

Endogenous central calcitonin receptor agonist

Endogenous central calcitonin (CT) receptor agonist that stimulates cAMP formation at a potency 350-fold greater than CT (ED50 values are 0.2 and 71 nM respectively). Displays no activity at calcitonin-gene related peptide (CGRP) and adrenomedullin receptors. Inhibits formation of multinuclear osteoclasts with similar efficacy to CT in vitro. Suppresses food intake and increases body temperature in free-feeding rats, and significantly decreases plasma calcium levels in vivo.

C175H294N54O49S5

4098.88

Calcitonin receptor-stimulating peptide-1