INH1 | Tocris Bioscience 3551 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

INH1

catalog :

3551

quantity :

10 mg (also 50 mg)

price :

136 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Linton A, Cheng Y, Griggs K, Schedlich L, Kirschner M, Gattani S, et al. An RNAi-based screen reveals PLK1, CDK1 and NDC80 as potential therapeutic targets in malignant pleural mesothelioma. Br J Cancer. 2014;110:510-9 pubmed publisher
Wu G, Qiu X, Zhou L, Zhu J, Chamberlin R, Lau J, et al. Small molecule targeting the Hec1/Nek2 mitotic pathway suppresses tumor cell growth in culture and in animal. Cancer Res. 2008;68:8393-9 pubmed publisher

product information

brand :

Tocris

master code :

3551

SKU :

3551/10

product name :

INH1

description :

Hec1 inhibitor; causes arrest of mitosis

target :

Mitosis-Related Compounds

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

344.86

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Hec1 inhibitor. Binds Hec1, inhibiting its association with Nek2 and kinetochores. Causes arrest of mitosis and inhibits proliferation in breast cancer cell lines (GI50= 10 - 20 M).

catalog number base :

3551

product keywords :

Hec1 inhibitors inhibits mitosis arrests Mitosis 3551,

extended description :

Hec1 inhibitor; causes arrest of mitosis

chemical name text :

N-[4-(2,4-Dimethylphenyl)-2-thiazolyl]benzamide hydrochloride

formula :

C 18 H 16 N 2 OS.HCl

formula text :

C18H16N2OS.HCl

cas num :

1780260-01-6

2020 USD :

136

2021 USD :

136 USD

storage :

Desiccate at +4°C

more info or order :

Tocris Bioscience product webpage