product summary
Loading...
company name :
Tocris Bioscience
product type :
chemical
product name :
Melatonin
catalog :
3550/50
quantity :
50 mg
price :
97 USD
more info or order :
citations: 10
Reference
Ghareghani M, Farhadi Z, Rivest S, Zibara K. PDK4 Inhibition Ameliorates Melatonin Therapy by Modulating Cerebral Metabolism and Remyelination in an EAE Demyelinating Mouse Model of Multiple Sclerosis. Front Immunol. 2022;13:862316 pubmed publisher
Zhang J, Tang J, Liu J, Yan B, Yan B, Huang M, et al. Melatonin Promotes Heterotopic Ossification Through Regulation of Endothelial-Mesenchymal Transition in Injured Achilles Tendons in Rats. Front Cell Dev Biol. 2021;9:629274 pubmed publisher
Au C, Furness J, Britt K, Oshchepkova S, Ladumor H, Soo K, et al. Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531. elife. 2020;9: pubmed publisher
Akoume M, Elbakry M, Veillette M, Franco A, Nada D, Labelle H, et al. A Differential Hypofunctionality of Gαi Proteins Occurs in Adolescent Idiopathic Scoliosis and Correlates with the Risk of Disease Progression. Sci Rep. 2019;9:10074 pubmed publisher
Fernandes J, Aoki J, Maia Acuña S, Zampieri R, Markus R, Floeter Winter L, et al. Melatonin and Leishmania amazonensis Infection Altered miR-294, miR-30e, and miR-302d Impacting on Tnf, Mcp-1, and Nos2 Expression. Front Cell Infect Microbiol. 2019;9:60 pubmed publisher
Hou B, Fu Y, Weng C, Liu W, Zhao C, Yin Z. Homeostatic Plasticity Mediated by Rod-Cone Gap Junction Coupling in Retinal Degenerative Dystrophic RCS Rats. Front Cell Neurosci. 2017;11:98 pubmed publisher
Costa L, Pellacani C, Dao K, Kavanagh T, Roqué P. The brominated flame retardant BDE-47 causes oxidative stress and apoptotic cell death in vitro and in vivo in mice. Neurotoxicology. 2015;48:68-76 pubmed publisher
Chen C, Fichna J, Laudon M, Storr M. Antinociceptive effects of novel melatonin receptor agonists in mouse models of abdominal pain. World J Gastroenterol. 2014;20:1298-304 pubmed publisher
Huang S, Giordano G, Costa L. Comparative cytotoxicity and intracellular accumulation of five polybrominated diphenyl ether congeners in mouse cerebellar granule neurons. Toxicol Sci. 2010;114:124-32 pubmed publisher
Giordano G, Kavanagh T, Costa L. Neurotoxicity of a polybrominated diphenyl ether mixture (DE-71) in mouse neurons and astrocytes is modulated by intracellular glutathione levels. Toxicol Appl Pharmacol. 2008;232:161-8 pubmed publisher
product information
brand :
Tocris
master code :
3550
SKU :
3550/50
product name :
Melatonin
unit size :
50 mg
seo description :
Endogenous hormone; agonist at MT1 and MT2
target :
Melatonin (MT) Receptor Agonists
category :
Small Molecules
purity :
99%
observed molecular weight :
232.28
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Melatonin is an endogenous hormone that acts as an agonist at melatonin receptors MT1 and MT2. Exhibits a prominent role in the control of circadian rhythm, displays immunomodulatory activity and acts as a powerful antioxidant in vivo .
top caption :
Endogenous hormone; agonist at MT1 and MT2
extended description :
Endogenous hormone; agonist at MT1 and MT2
chemical name text :
N-Acetyl-5-methoxytryptamine
formula :
C13H16N2O2
formula text :
C13H16N2O2
cas num :
73-31-4
USD :
97 USD
product details :
Endogenous hormone; agonist at MT1 and MT2
storage :
Store at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK