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company name :
Tocris Bioscience
product type :
chemical
product name :
Serotonin hydrochloride
catalog :
3547/50
quantity :
50 mg
price :
112 USD
more info or order :
citations: 28
Reference
Gumpper R, Fay J, Roth B. Molecular insights into the regulation of constitutive activity by RNA editing of 5HT2C serotonin receptors. Cell Rep. 2022;40:111211 pubmed publisher
Kim S, Wallace M, El Rifai M, Knudsen A, Sabatini B. Co-packaging of opposing neurotransmitters in individual synaptic vesicles in the central nervous system. Neuron. 2022;110:1371-1384.e7 pubmed publisher
Hachoumi L, Rensner R, Richmond C, Picton L, Zhang H, Sillar K. Bimodal modulation of short-term motor memory via dynamic sodium pumps in a vertebrate spinal cord. Curr Biol. 2022;32:1038-1048.e2 pubmed publisher
Yoo E, Li L, Jia L, Lord C, Lee C, Birnbaum S, et al. Gαi/o-coupled Htr2c in the paraventricular nucleus of the hypothalamus antagonizes the anorectic effect of serotonin agents. Cell Rep. 2021;37:109997 pubmed publisher
Leon R, Borner T, Stein L, Urrutia N, De Jonghe B, Schmidt H, et al. Activation of PPG neurons following acute stressors differentially involves hindbrain serotonin in male rats. Neuropharmacology. 2021;187:108477 pubmed publisher
Xing L, Kalebic N, Namba T, Vaid S, Wimberger P, Huttner W. Serotonin Receptor 2A Activation Promotes Evolutionarily Relevant Basal Progenitor Proliferation in the Developing Neocortex. Neuron. 2020;108:1113-1129.e6 pubmed publisher
Kweon H, Gu S, Witham E, Dhara M, Yu H, Mandon E, et al. NACHO Engages N-Glycosylation ER Chaperone Pathways for α7 Nicotinic Receptor Assembly. Cell Rep. 2020;32:108025 pubmed publisher
Wu Q, Kuca K, Nepovimova E, Wu W. Type A Trichothecene Diacetoxyscirpenol-Induced Emesis Corresponds to Secretion of Peptide YY and Serotonin in Mink. Toxins (Basel). 2020;12: pubmed publisher
Kumar A, Russell R, Pifer R, Menezes Garcia Z, Cuesta S, Narayanan S, et al. The Serotonin Neurotransmitter Modulates Virulence of Enteric Pathogens. Cell Host Microbe. 2020;28:41-53.e8 pubmed publisher
Liu C, Meng Z, Wiggin T, Yu J, Reed M, Guo F, et al. A Serotonin-Modulated Circuit Controls Sleep Architecture to Regulate Cognitive Function Independent of Total Sleep in Drosophila. Curr Biol. 2019;29:3635-3646.e5 pubmed publisher
Patzke C, Brockmann M, Dai J, Gan K, Grauel M, Fenske P, et al. Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses. Cell. 2019;179:498-513.e22 pubmed publisher
Brandenburg C, Blatt G. Differential serotonin transporter (5-HTT) and 5-HT2 receptor density in limbic and neocortical areas of adults and children with autism spectrum disorders: implications for selective serotonin reuptake inhibitor efficacy. J Neurochem. 2019;151:642-655 pubmed publisher
Leon R, Borner T, Reiner D, Stein L, Lhamo R, De Jonghe B, et al. Hypophagia induced by hindbrain serotonin is mediated through central GLP-1 signaling and involves 5-HT2C and 5-HT3 receptor activation. Neuropsychopharmacology. 2019;: pubmed publisher
Feng J, Zhang C, Lischinsky J, Jing M, Zhou J, Wang H, et al. A Genetically Encoded Fluorescent Sensor for Rapid and Specific In Vivo Detection of Norepinephrine. Neuron. 2019;: pubmed publisher
Ye H, Adane B, Khan N, Alexeev E, Nusbacher N, Minhajuddin M, et al. Subversion of Systemic Glucose Metabolism as a Mechanism to Support the Growth of Leukemia Cells. Cancer Cell. 2018;34:659-673.e6 pubmed publisher
Matsui A, Alvarez V. Cocaine Inhibition of Synaptic Transmission in the Ventral Pallidum Is Pathway-Specific and Mediated by Serotonin. Cell Rep. 2018;23:3852-3863 pubmed publisher
Szabo A, Gogolak P, Koncz G, Foldvari Z, Pazmandi K, Miltner N, et al. Immunomodulatory capacity of the serotonin receptor 5-HT2B in a subset of human dendritic cells. Sci Rep. 2018;8:1765 pubmed publisher
Hooper C, Delaney C, Streeter T, Yarboro M, Poole S, Brown N, et al. Selective serotonin reuptake inhibitor exposure constricts the mouse ductus arteriosus in utero. Am J Physiol Heart Circ Physiol. 2016;311:H572-81 pubmed publisher
Yin L, Rasch M, He Q, Wu S, Dou F, Shu Y. Selective Modulation of Axonal Sodium Channel Subtypes by 5-HT1A Receptor in Cortical Pyramidal Neuron. Cereb Cortex. 2017;27:509-521 pubmed publisher
Gerhold K, Drdla Schutting R, Honsek S, Forsthuber L, Sandkühler J. Pronociceptive and Antinociceptive Effects of Buprenorphine in the Spinal Cord Dorsal Horn Cover a Dose Range of Four Orders of Magnitude. J Neurosci. 2015;35:9580-94 pubmed publisher
Bhattachariya A, Dahan D, Ekman M, Boettger T, Braun T, Swärd K, et al. Spontaneous activity and stretch-induced contractile differentiation are reduced in vascular smooth muscle of miR-143/145 knockout mice. Acta Physiol (Oxf). 2015;215:133-43 pubmed publisher
Bocchio M, Fucsina G, Oikonomidis L, McHugh S, Bannerman D, Sharp T, et al. Increased Serotonin Transporter Expression Reduces Fear and Recruitment of Parvalbumin Interneurons of the Amygdala. Neuropsychopharmacology. 2015;40:3015-26 pubmed publisher
Haynes P, Christmann B, Griffith L. A single pair of neurons links sleep to memory consolidation in Drosophila melanogaster. elife. 2015;4: pubmed publisher
Bracha S, Viall A, Goodall C, Stang B, Ruaux C, Seguin B, et al. The expression and role of serotonin receptor 5HTR2A in canine osteoblasts and an osteosarcoma cell line. BMC Vet Res. 2013;9:251 pubmed publisher
Daftary S, Calderon G, Rios M. Essential role of brain-derived neurotrophic factor in the regulation of serotonin transmission in the basolateral amygdala. Neuroscience. 2012;224:125-34 pubmed publisher
Robery S, Mukanowa J, Percie du Sert N, Andrews P, Williams R. Investigating the effect of emetic compounds on chemotaxis in Dictyostelium identifies a non-sentient model for bitter and hot tastant research. PLoS ONE. 2011;6:e24439 pubmed publisher
Rawls S, Shah H, Ayoub G, Raffa R. 5-HT(1A)-like receptor activation inhibits abstinence-induced methamphetamine withdrawal in planarians. Neurosci Lett. 2010;484:113-7 pubmed publisher
Yang N, Liu S, Zheng L, Ji T, Li Y, Mi X, et al. Activation of submucosal 5-HT(3) receptors elicits a somatostatin-dependent inhibition of ion secretion in rat colon. Br J Pharmacol. 2010;159:1623-5 pubmed publisher
product information
brand :
Tocris
master code :
3547
SKU :
3547/50
product name :
Serotonin hydrochloride
unit size :
50 mg
seo description :
Endogenous 5-HT receptor agonist
target :
Non-selective 5-HT Receptor Agonists
category :
Small Molecules
purity :
98%
observed molecular weight :
212.68
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Serotonin hydrochloride is an endogenous agonist at 5-HT receptors and endogenous substrate for 5-HT transporters. Neurotransmitter that has roles in regulation of mood, emesis, sexuality, sleep and appetite in vivo .
top caption :
Endogenous 5-HT receptor agonist
extended description :
Endogenous 5-HT receptor agonist
chemical name text :
3-(2-Aminoethyl)-1H-indol-5-ol hydrochloride
formula :
C10H12N2O.HCl
formula text :
C10H12N2O.HCl
cas num :
153-98-0
USD :
112 USD
product details :
Endogenous 5-HT receptor agonist
alt names :
5-Hydroxytryptamine,5-HT
storage :
Store at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK