product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Histamine dihydrochloride
catalog :
3545/50
quantity :
50 mg
price :
99 USD
more info or order :
citations: 10
Reference
Sheu S, Upadhyayula S, Dupuy V, Pang S, Deng F, Wan J, et al. A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility. Cell. 2022;185:3390-3407.e18 pubmed publisher
Boccella S, Guida F, Iannotta M, Iannotti F, Infantino R, Ricciardi F, et al. 2-Pentadecyl-2-oxazoline ameliorates memory impairment and depression-like behaviour in neuropathic mice: possible role of adrenergic alpha2- and H3 histamine autoreceptors. Mol Brain. 2021;14:28 pubmed publisher
Patzke C, Brockmann M, Dai J, Gan K, Grauel M, Fenske P, et al. Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses. Cell. 2019;179:498-513.e22 pubmed publisher
Feng J, Zhang C, Lischinsky J, Jing M, Zhou J, Wang H, et al. A Genetically Encoded Fluorescent Sensor for Rapid and Specific In Vivo Detection of Norepinephrine. Neuron. 2019;: pubmed publisher
Grimsey N, Lin Y, Narala R, Rada C, Mejia Pena H, Trejo J. G protein-coupled receptors activate p38 MAPK via a non-canonical TAB1-TAB2- and TAB1-TAB3-dependent pathway in endothelial cells. J Biol Chem. 2019;294:5867-5878 pubmed publisher
Fan J, Ray P, Lu Y, Kaur G, Schwarz J, Wan L. Cell chirality regulates intercellular junctions and endothelial permeability. Sci Adv. 2018;4:eaat2111 pubmed publisher
Chen X, Deng H, Churchill M, Luchsinger L, Du X, Chu T, et al. Bone Marrow Myeloid Cells Regulate Myeloid-Biased Hematopoietic Stem Cells via a Histamine-Dependent Feedback Loop. Cell Stem Cell. 2017;21:747-760.e7 pubmed publisher
Gerhold K, Drdla Schutting R, Honsek S, Forsthuber L, Sandkühler J. Pronociceptive and Antinociceptive Effects of Buprenorphine in the Spinal Cord Dorsal Horn Cover a Dose Range of Four Orders of Magnitude. J Neurosci. 2015;35:9580-94 pubmed publisher
Femenía T, Magara S, DuPont C, Lindskog M. Hippocampal-Dependent Antidepressant Action of the H3 Receptor Antagonist Clobenpropit in a Rat Model of Depression. Int J Neuropsychopharmacol. 2015;18: pubmed publisher
Melchior B, Frangos J. G?q/11-mediated intracellular calcium responses to retrograde flow in endothelial cells. Am J Physiol Cell Physiol. 2012;303:C467-73 pubmed publisher
product information
brand :
Tocris
master code :
3545
SKU :
3545/50
product name :
Histamine dihydrochloride
unit size :
50 mg
seo description :
Endogenous histamine receptor agonist
target :
Histamine H1 Receptor Agonists
category :
Small Molecules
observed molecular weight :
184.07
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Histamine dihydrochloride is an endogenous agonist at histamine receptors (H1-4). Released from mast cells and basophils and exhibits inflammatory, vasodilatory and bronchoconstrictory activity. Stimulates gastric acid secretion and acts as a neurotransmitter in vivo .
top caption :
Endogenous histamine receptor agonist
extended description :
Endogenous histamine receptor agonist
chemical name text :
2-(4-Imidazolyl)ethylamine dihydrochloride
formula :
C5H9N3.2HCl
formula text :
C5H9N3.2HCl
cas num :
56-92-8
USD :
99 USD
product details :
Endogenous histamine receptor agonist
storage :
Desiccate at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK