Orlistat | Tocris Bioscience 3540 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Orlistat

catalog :

3540

quantity :

10 mg (also 50 mg)

price :

64 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Argueta D, Perez P, Makriyannis A, DiPatrizio N. Cannabinoid CB1 Receptors Inhibit Gut-Brain Satiation Signaling in Diet-Induced Obesity. Front Physiol. 2019;10:704 pubmed publisher
Xiao L, Priest M, Kozorovitskiy Y. Oxytocin functions as a spatiotemporal filter for excitatory synaptic inputs to VTA dopamine neurons. elife. 2018;7: pubmed publisher
Musella A, Fresegna D, Rizzo F, Gentile A, Bullitta S, De Vito F, et al. A novel crosstalk within the endocannabinoid system controls GABA transmission in the striatum. Sci Rep. 2017;7:7363 pubmed publisher
Caiati M, Sivakumaran S, Lanore F, Mulle C, Richard E, Verrier D, et al. Developmental regulation of CB1-mediated spike-time dependent depression at immature mossy fiber-CA3 synapses. Sci Rep. 2012;2:285 pubmed publisher
Breunig E, Manzini I, Piscitelli F, Gutermann B, Di Marzo V, Schild D, et al. The endocannabinoid 2-arachidonoyl-glycerol controls odor sensitivity in larvae of Xenopus laevis. J Neurosci. 2010;30:8965-73 pubmed publisher

product information

brand :

Tocris

master code :

3540

SKU :

3540/10

product name :

Orlistat

description :

Pancreatic, gastric and carboxylester lipase inhibitor; antiobesity and antihypercholesterolemic activity

target :

Lipase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

495.73

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Hypolipemic pancreatic, gastric and carboxylester lipase inhibitor. Exhibits no activity at phospholipase A2, liver esterase, trypsin and chymotrypsin. Inhibits the thioesterase domain of fatty acid synthase, leading to cell cycle arrest at the G1/S boundary in vitro . Prevents the absorption of approximately one third of fat from food and exhibits progastrokinetic, antiobesity and antihypercholesterolemic activity in vivo .

catalog number base :

3540

product keywords :

Fatty acid synthases inhibits inhibitors pancreatic gastric carboxylester lipases Pancreatic antiobesity antihypercholesterolemic antihypercholesterolaemic activity Synthases Esterases FAS FASN Lipases Fatty Acid Synthase 3540,

extended description :

Pancreatic, gastric and carboxylester lipase inhibitor; antiobesity and antihypercholesterolemic activity

chemical name text :

N-Formyl-L-leucine (1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester

formula :

C 29 H 53 NO 5

formula text :

C29H53NO5

cas num :

96829-58-2

2020 USD :

2021 USD :

64 USD

storage :

Desiccate at +4°C

more info or order :

Tocris Bioscience product webpage