product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
HQL 79
catalog :
3530/10
quantity :
10 mg (also 50 mg)
price :
231 USD
more info or order :
citations: 2
Reference
Song W, Ricciotti E, Liang X, Grosser T, Grant G, Fitzgerald G. Lipocalin-Like Prostaglandin D Synthase but Not Hemopoietic Prostaglandin D Synthase Deletion Causes Hypertension and Accelerates Thrombogenesis in Mice. J Pharmacol Exp Ther. 2018;367:425-432 pubmed publisher
Chen Y, Yu H, Pask A, Shaw G, Renfree M. Prostaglandin D2 Regulates SOX9 Nuclear Translocation during Gonadal Sex Determination in Tammar Wallaby, Macropus eugenii. Sex Dev. 2017;11:143-150 pubmed publisher
product information
brand :
Tocris, a Bio-Techne Brand
catalog number base :
3530
SKU :
3530/10
product name :
HQL 79
Description :
Human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor
target :
Synthase/Synthetase Inhibitors
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
99%
observed molecular weight :
377.48
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
HQL 79 is an orally active and specific inhibitor of human hematopoietic prostaglandin D synthase (H-PGDS) (IC50 = 6 M). Antiallergic and anti-inflammatory; displays antiasthmatic activity and potent antihistaminic properties in vivo .
extended description :
Human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor
chemical name text :
4-(Diphenylmethoxy)-1-(3-2H-tetrazol-5-yl)propyl]-piperidine
formula :
C 22 H 27 N 5 O
formula text :
C22H27N5O
cas num :
162641-16-9
USD :
231 USD
product details :
Human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK