SB 243213 dihydrochloride | Tocris Bioscience 3527 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SB 243213 dihydrochloride

catalog :

3527

quantity :

10 mg (also 50 mg)

price :

180 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Ward R, Pediani J, Godin A, Milligan G. Regulation of oligomeric organization of the serotonin 5-hydroxytryptamine 2C (5-HT2C) receptor observed by spatial intensity distribution analysis. J Biol Chem. 2015;290:12844-57 pubmed publisher

product information

brand :

Tocris

master code :

3527

SKU :

3527/10

product name :

SB 243213 dihydrochloride

description :

Selective 5-HT2C inverse agonist

target :

5-HT2C Receptor Inverse Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

501.33

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective 5-HT2C inverse agonist (pKb = 9.8). Displays selectivity over other 5-HT2 subtypes (pKi values are 6.8, 7.0 and 9.0 for 5-HT2A, 5-HT2B and 5-HT2C respectively); also exhibits 100-fold selectivity over 50 other receptors, ion channels and enzymes. Displays anxiolytic activity in rat models.

catalog number base :

3527

product keywords :

SB243213 dihydrochloride selective 5-ht3 inverse agonists serotonergics 5-HT2C Receptors 3527,

extended description :

Selective 5-HT2C inverse agonist

chemical name text :

2,3-Dihydro-5-methyl-N-[6-[(2-methyl-3-pyridinyl)oxy]-3-pyridinyl]-6-(trifluoromethyl)-1H-Indole-1-carboxamide dihydrochloride

formula :

C 22 H 19 F 3 N 4 O 2 .2HCl

formula text :

C22H19F3N4O2.2HCl

cas num :

1780372-25-9

2020 USD :

180

2021 USD :

180 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage