Sirtinol | Tocris Bioscience 3521 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Sirtinol

catalog :

3521

quantity :

10 mg (also 50 mg)

price :

191 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Stoney P, Helfer G, Rodrigues D, Morgan P, McCaffery P. Thyroid hormone activation of retinoic acid synthesis in hypothalamic tanycytes. Glia. 2016;64:425-39 pubmed publisher
Balaiya S, Khetpal V, Chalam K. Hypoxia initiates sirtuin1-mediated vascular endothelial growth factor activation in choroidal endothelial cells through hypoxia inducible factor-2?. Mol Vis. 2012;18:114-20 pubmed
Paffett M, Lucas S, Campen M. Resveratrol reverses monocrotaline-induced pulmonary vascular and cardiac dysfunction: a potential role for atrogin-1 in smooth muscle. Vascul Pharmacol. 2012;56:64-73 pubmed publisher

product information

brand :

Tocris

master code :

3521

SKU :

3521/10

product name :

Sirtinol

description :

Selective sirtuin family deacetylase inhibitor

target :

Class III Histone Deacetylases Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

394.47

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Cell-permeable, selective sirtuin deacetylase inhibitor (IC50 values are 38, 68 and 131 M at SIRT2, Sir2p and SIRT1 respectively) that has no effect on HDAC1 activity. Significantly decreases growth and viability of PCa and HEK293T cells in vitro .

catalog number base :

3521

product keywords :

Selective sirtuin family deacetylases inhibitors inhibits Sirtuin Sir2-like Family Class III HDACs (Sirtuins) 3521,

extended description :

Selective sirtuin family deacetylase inhibitor

chemical name text :

2-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]-N-(1-phenylethyl)benzamide

formula :

C 26 H 22 N 2 O 2

formula text :

C26H22N2O2

cas num :

410536-97-9

2020 USD :

185

2021 USD :

191 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage