AM 80 | Tocris Bioscience 3507 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AM 80

catalog :

3507

quantity :

10 mg (also 50 mg)

price :

205 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Duprey Díaz M, Blagburn J, Blanco R. Exogenous Modulation of Retinoic Acid Signaling Affects Adult RGC Survival in the Frog Visual System after Optic Nerve Injury. PLoS ONE. 2016;11:e0162626 pubmed publisher

product information

brand :

Tocris

master code :

3507

SKU :

3507/10

product name :

AM 80

description :

RAR agonist; anticancer agent

target :

Retinoic Acid Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

351.44

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Retinoic acid receptor (RAR ) agonist that induces differentiation (ED50 = 0.79 nM) and apoptosis of HL-60 cells in vitro . Exhibits antiproliferative effects against a variety of human tumor cells lines (mean values of 35, 40 and 60% growth inhibition at 0.1, 1 and 10 M respectively) and displays anticancer activity against acute promyelocytic leukemia in vivo .

catalog number base :

3507

product keywords :

RAR RARalpha agonists anticancer Retinoic Acid Receptors AM80 Tamibarotene Retinoic Acid Receptors 3507,

extended description :

RAR agonist; anticancer agent

chemical name text :

4-[[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)amino]carbonyl]benzoic acid

formula :

C 22 H 25 NO 3

formula text :

C22H25NO3

cas num :

94497-51-5

2020 USD :

197

2021 USD :

205 USD

alt names :

Tamibarotene

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage