NVP DPP 728 dihydrochloride | Tocris Bioscience 3506 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NVP DPP 728 dihydrochloride

catalog :

3506

quantity :

10 mg (also 50 mg)

price :

175 USD

citations: 1

Reference
Inoue T, Wang J, Higashiyama M, Rudenkyy S, Higuchi K, Guth P, et al. Dipeptidyl peptidase IV inhibition potentiates amino acid- and bile acid-induced bicarbonate secretion in rat duodenum. Am J Physiol Gastrointest Liver Physiol. 2012;303:G810-6 pubmed publisher

product information

brand :

Tocris

master code :

3506

SKU :

3506/10

product name :

NVP DPP 728 dihydrochloride

description :

Potent, orally active dipeptidyl peptidase IV (DPP-IV) inhibitor

target :

DPPIV/CD26 Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

97%

observed molecular weight :

371.27

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent, orally active dipeptidyl peptidase (DPP)-IV inhibitor (Ki = 11 nM, IC50 = 14 nM) that displays 15 000-fold selectivity over DPP-II and a range of proline-cleaving proteases. Exhibits antidiabetic activity in vivo ; improves glucose tolerance, increases glucagon-like peptide 1 (GLP-1) and insulin levels, augments insulin secretion and GLUT2 levels, and reduces (preserves) islet size.

catalog number base :

3506

product keywords :

Potent orally active DPP-IV inhibitors inhibits Dipeptidyl Peptidase IV Proteinases Proteases NVPDPP728 dihydrochloride DPP4 Dipeptidyl Peptidase IV (DPP-IV) Glucose Transporters 3506,

extended description :

Potent, orally active dipeptidyl peptidase IV (DPP-IV) inhibitor

chemical name text :

6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbononitrile dihydrochloride

formula :

C 15 H 18 N 6 O.2HCl

formula text :

C15H18N6O.2HCl

cas num :

207556-62-5

2020 USD :

194

2021 USD :

175 USD

storage :

Store at -20°C