Epothilone B | Tocris Bioscience 3502 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Epothilone B

catalog :

3502

quantity :

100 ug

price :

335 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

3502

SKU :

3502/100U

product name :

Epothilone B

description :

Microtubule stabilization agent; promotes tubulin polymerization

target :

Microtubule Binding Compounds

category :

Small Molecules

unit size :

100 ug

purity :

98%

observed molecular weight :

507.68

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Microtubule stabilization agent that promotes tubulin polymerization and induces G2-M cell cycle arrest (EC50 = 32 nM in HeLa cells). Inhibits proliferation of human carcinoma cell lines in vitro , including MDR cells overexpressing the P-glycoprotein efflux pump. Exhibits potent cytotoxicity in MCF-7 and A549 cells (EC50 values are 0.3 and 2.7 nM respectively). Inhibits growth of HCT-15 tumors in mice in vivo .

catalog number base :

3502

product keywords :

Microtubule stabilization agent promotes tubulin polymerization G2-M cell cycle arrest Tau Tubulin Mitosis EpothiloneB Patupilone Microtubules Mitosis Cell Cycle Inhibitors 3502,

extended description :

Microtubule stabilization agent; promotes tubulin polymerization

chemical name text :

(1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12,16-pentamethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione

formula :

C 27 H 41 NO 6 S

formula text :

C27H41NO6S

cas num :

152044-54-7

2020 USD :

335

2021 USD :

335 USD

alt names :

Patupilone

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage