product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
TRAP-6
catalog :
3497
quantity :
5 mg
price :
229 USD
more info or order :
citations: 5
Reference
Gockel L, Ponert J, Schwarz S, Schlesinger M, Bendas G. The Low Molecular Weight Heparin Tinzaparin Attenuates Platelet Activation in Terms of Metastatic Niche Formation by Coagulation-Dependent and Independent Pathways. Molecules. 2018;23: pubmed publisher
Ponert J, Gockel L, Henze S, Schlesinger M. Unfractionated and Low Molecular Weight Heparin Reduce Platelet Induced Epithelial-Mesenchymal Transition in Pancreatic and Prostate Cancer Cells. Molecules. 2018;23: pubmed publisher
Dhenge A, Limbkar K, Melinkeri S, Kale V, Limaye L. Arachidonic acid and Docosahexanoic acid enhance platelet formation from human apheresis-derived CD34+ cells. Cell Cycle. 2017;16:979-990 pubmed publisher
Tripathi T, Abdi M, Alizadeh H. Protease-activated receptor 2 (PAR2) is upregulated by Acanthamoeba plasminogen activator (aPA) and induces proinflammatory cytokine in human corneal epithelial cells. Invest Ophthalmol Vis Sci. 2014;55:3912-21 pubmed publisher
Yan J, Manaenko A, Chen S, Klebe D, Ma Q, Caner B, et al. Role of SCH79797 in maintaining vascular integrity in rat model of subarachnoid hemorrhage. Stroke. 2013;44:1410-7 pubmed publisher
product information
brand :
Tocris
master code :
3497
SKU :
3497/5
product name :
TRAP-6
description :
PAR1 peptide fragment (residues 42-47); acts as a PAR1 agonist
target :
Protease-Activated Receptor Agonists
category :
Peptides
unit size :
5 mg
observed molecular weight :
748.88
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
Peptide fragment (residues 42-47) of protease-activated receptor 1 (PAR1) that acts as a PAR1 agonist. Stimulates platelet aggregation (EC50 = 0.8 M), promotes intracellular Ca2+ mobilization and induces rapid phosphodiesterase 3A (PDE3A) phosphorylation in vitro .
catalog number base :
3497
product keywords :
PAR1 peptide fragment residues 42-47 agonists Receptors Protease-Activated proteinase-activated Thrombin receptor activator peptide6 Thrombin receptor activator peptide 6 Protease-Activated Receptors 3497,
extended description :
PAR1 peptide fragment (residues 42-47); acts as a PAR1 agonist
formula :
C 34 H 56 N 10 O 9
formula text :
C34H56N10O9
cas num :
141136-83-6
2020 USD :
218
2021 USD :
229 USD
alt names :
Thrombin receptor activator peptide 6
storage :
Desiccate at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK