TRAP-6 | Tocris Bioscience 3497/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TRAP-6

catalog :

3497/5

quantity :

5 mg

price :

297 USD

more info or order :

Tocris Bioscience product webpage

citations: 8

Reference
Elenbaas J, Pudupakkam U, Ashworth K, Kang C, Patel V, Santana K, et al. SVEP1 is an endogenous ligand for the orphan receptor PEAR1. Nat Commun. 2023;14:850 pubmed publisher
Giannella A, Ceolotto G, Radu C, Cattelan A, Iori E, Benetti A, et al. PAR-4/Ca2+-calpain pathway activation stimulates platelet-derived microparticles in hyperglycemic type 2 diabetes. Cardiovasc Diabetol. 2021;20:77 pubmed publisher
Gockel L, Ponert J, Schwarz S, Schlesinger M, Bendas G. The Low Molecular Weight Heparin Tinzaparin Attenuates Platelet Activation in Terms of Metastatic Niche Formation by Coagulation-Dependent and Independent Pathways. Molecules. 2018;23: pubmed publisher
Ponert J, Gockel L, Henze S, Schlesinger M. Unfractionated and Low Molecular Weight Heparin Reduce Platelet Induced Epithelial-Mesenchymal Transition in Pancreatic and Prostate Cancer Cells. Molecules. 2018;23: pubmed publisher
Dhenge A, Limbkar K, Melinkeri S, Kale V, Limaye L. Arachidonic acid and Docosahexanoic acid enhance platelet formation from human apheresis-derived CD34+ cells. Cell Cycle. 2017;16:979-990 pubmed publisher
Tripathi T, Abdi M, Alizadeh H. Protease-activated receptor 2 (PAR2) is upregulated by Acanthamoeba plasminogen activator (aPA) and induces proinflammatory cytokine in human corneal epithelial cells. Invest Ophthalmol Vis Sci. 2014;55:3912-21 pubmed publisher
Yan J, Manaenko A, Chen S, Klebe D, Ma Q, Caner B, et al. Role of SCH79797 in maintaining vascular integrity in rat model of subarachnoid hemorrhage. Stroke. 2013;44:1410-7 pubmed publisher
Rius C, Piqueras L, Gonzalez Navarro H, Albertos F, Company C, Lopez Gines C, et al. Arterial and venous endothelia display differential functional fractalkine (CX3CL1) expression by angiotensin-II. Arterioscler Thromb Vasc Biol. 2013;33:96-104 pubmed publisher

product information

brand :

Tocris

catalog number base :

3497

SKU :

3497/5

product name :

TRAP-6

units size :

5 mg

description :

PAR1 peptide fragment (residues 42-47); acts as a PAR1 agonist

target :

Protease-Activated Receptor Agonists

category :

Peptides

purity :

95%

observed molecular weight :

748.88

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

TRAP-6 is a peptide fragment (residues 42-47) of protease-activated receptor 1 (PAR1) that acts as a PAR1 agonist. Stimulates platelet aggregation (EC50 = 0.8 M), promotes intracellular Ca2+ mobilization and induces rapid phosphodiesterase 3A (PDE3A) phosphorylation in vitro .

top caption :

PAR1 peptide fragment (residues 42-47); acts as a PAR1 agonist

extended description :

PAR1 peptide fragment (residues 42-47); acts as a PAR1 agonist

formula :

C34H56N10O9

formula text :

C34H56N10O9

cas num :

141136-83-6

USD :

297 USD

product details :

PAR1 peptide fragment (residues 42-47); acts as a PAR1 agonist

alt names :

Thrombin receptor activator peptide 6

storage :

Store at -20Â°C

more info or order :

Tocris Bioscience product webpage