Fludarabine | Tocris Bioscience 3495 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Fludarabine

catalog :

3495

quantity :

10 mg (also 50 mg)

price :

151 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Odendall C, Dixit E, Stavru F, Bierne H, Franz K, Durbin A, et al. Diverse intracellular pathogens activate type III interferon expression from peroxisomes. Nat Immunol. 2014;15:717-26 pubmed publisher
Robinson T, Liu J, Vizeacoumar F, Sun T, MacLean N, Egan S, et al. RB1 status in triple negative breast cancer cells dictates response to radiation treatment and selective therapeutic drugs. PLoS ONE. 2013;8:e78641 pubmed publisher

product information

brand :

Tocris

master code :

3495

SKU :

3495/10

product name :

Fludarabine

description :

Purine analog; inhibits DNA synthesis

target :

DNA, RNA and Protein Synthesis Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

285.23

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Purine analog that inhibits DNA synthesis. Exhibits antiproliferative activity (IC50 = 1.54 M in RPMI cells) and triggers apoptosis through increasing Bax and decreasing Bid, XIAP and survivin expression. Inhibits cytokine-induced activation of STAT1 and STAT1-dependent gene transcription in lymphocytes. Also displays anticancer activity against hematological malignancies in vivo .

catalog number base :

3495

product keywords :

Purine analog inhibits inhibitors DNA synthesis Proapoptotic increases Bax decreases Bid XIAP survivin expression Apoptosis Inducer STAT1 chemotherapeutics DNA, RNA and Protein Synthesis Apoptosis Inducers STAT 3495,

extended description :

Purine analog; inhibits DNA synthesis

chemical name text :

9- -D-Arabinofuranosyl-2-fluoro-9H-purin-6-amine

formula :

C 10 H 12 FN 5 O 4

formula text :

C10H12FN5O4

cas num :

21679-14-1

2020 USD :

145

2021 USD :

151 USD

storage :

Desiccate at +4°C

more info or order :

Tocris Bioscience product webpage