Cyclosomatostatin | Tocris Bioscience 3493/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Cyclosomatostatin

catalog :

3493/1

quantity :

1 mg

price :

253 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Watamura N, Kakiya N, Nilsson P, Tsubuki S, Kamano N, Takahashi M, et al. Somatostatin-evoked Aβ catabolism in the brain: Mechanistic involvement of α-endosulfine-KATP channel pathway. Mol Psychiatry. 2021;: pubmed publisher
Rofo F, Ugur Yilmaz C, Metzendorf N, Gustavsson T, Beretta C, Erlandsson A, et al. Enhanced neprilysin-mediated degradation of hippocampal Aβ42 with a somatostatin peptide that enters the brain. Theranostics. 2021;11:789-804 pubmed publisher
Zhang T, Ahn K, Emerick B, Modarai S, Opdenaker L, Palazzo J, et al. APC mutations in human colon lead to decreased neuroendocrine maturation of ALDH+ stem cells that alters GLP-2 and SST feedback signaling: Clue to a link between WNT and retinoic acid signalling in colon cancer development. PLoS ONE. 2020;15:e0239601 pubmed publisher
Song Y, Hwang Y, Kim K, Lee H, Kim J, Maclachlan C, et al. Somatostatin enhances visual processing and perception by suppressing excitatory inputs to parvalbumin-positive interneurons in V1. Sci Adv. 2020;6:eaaz0517 pubmed publisher
Elliott A, Ustione A, Piston D. Somatostatin and insulin mediate glucose-inhibited glucagon secretion in the pancreatic Î±-cell by lowering cAMP. Am J Physiol Endocrinol Metab. 2015;308:E130-43 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

3493

SKU :

3493/1

product name :

Cyclosomatostatin

description :

Non-selective sst antagonist

target :

Somatostatin Receptor Antagonists

unit size :

1 mg

category :

Peptides

purity :

95%

storage :

Store at -20°C

observed molecular weight :

779.98

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Cyclosomatostatin is a non-selective somatostatin (sst) receptor antagonist. Blocks the effects of sst on airway -adrenergic function, CRF-induced suppression of gastric empyting, modulation of ACh release and growth hormone, insulin and glucagon release. Reported to act as an sst receptor agonist in human neuroblastoma cell line SH-SY5Y.

product keywords :

Non-Selective sst receptor antagonists Receptors Somatostatin Cyclo-(7-aminoheptanoyl-Phe-D-Trp-Lys-Thr[BZL]) Somatostatin Receptors 3493,

extended description :

Non-selective sst antagonist

formula :

C44H57N7O6

formula text :

C44H57N7O6

cas num :

84211-54-1

USD :

242

USD 2025 :

253 USD

product details :

Non-selective sst antagonist

alt names :

Cyclo-(7-aminoheptanoyl-Phe- D-Trp-Lys-Thr[BZL])

more info or order :

Tocris Bioscience product webpage