product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
ACTH (1-39)
catalog :
3492
quantity :
1 mg
price :
385 USD
more info or order :
citations: 3
Reference
Nepomuceno D, Kuei C, Dvorak C, Lovenberg T, Liu C, Bonaventure P. Re-evaluation of Adrenocorticotropic Hormone and Melanocyte Stimulating Hormone Activation of GPR139 in Vitro. Front Pharmacol. 2018;9:157 pubmed publisher
Nøhr A, Shehata M, Hauser A, Isberg V, Mokrosinski J, Andersen K, et al. The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and the conserved core motif HFRW. Neurochem Int. 2017;102:105-113 pubmed publisher
Martineau C, Martin Falstrault L, Brissette L, Moreau R. The atherogenic Scarb1 null mouse model shows a high bone mass phenotype. Am J Physiol Endocrinol Metab. 2014;306:E48-57 pubmed publisher
product information
brand :
Tocris
master code :
3492
SKU :
3492/1
product name :
ACTH (1-39)
description :
Potent endogenous MC2 agonist
target :
Melanocortin Receptor Agonists
category :
Peptides
unit size :
1 mg
observed molecular weight :
4541.1
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
Potent endogenous melanocortin receptor 2 (MC2) agonist (EC50 = 57 pM). Component of the hypothalamic-pituitary-adrenal (HPA) axis that stimulates glucocorticoid production and release from the adrenal cortex. Induces insulin resistance, promotes a proinflammatory profile and stimulates UCP-1 in adipocytes in vitro .
catalog number base :
3492
product keywords :
Potent endogenous MC2R agonists Receptors Melanocortin acethropan Adrenocorticotropic hormone (1-39) Melanocortin Receptors 3492,
extended description :
Potent endogenous MC2 agonist
formula :
C 207 H 308 N 56 O 58 S
formula text :
C207H308N56O58S
cas num :
12279-41-3
2020 USD :
370
2021 USD :
385 USD
alt names :
Adrenocorticotropic hormone (1-39)
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK