ACTH (1-39) | Tocris Bioscience 3492/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ACTH (1-39)

catalog :

3492/1

quantity :

1 mg

price :

493 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Piotrowska A, Starnowska Sokół J, Makuch W, Mika J, Witkowska E, Tymecka D, et al. Novel bifunctional hybrid compounds designed to enhance the effects of opioids and antagonize the pronociceptive effects of nonopioid peptides as potent analgesics in a rat model of neuropathic pain. Pain. 2021;162:432-445 pubmed publisher
Nepomuceno D, Kuei C, Dvorak C, Lovenberg T, Liu C, Bonaventure P. Re-evaluation of Adrenocorticotropic Hormone and Melanocyte Stimulating Hormone Activation of GPR139 in Vitro. Front Pharmacol. 2018;9:157 pubmed publisher
NÃ¸hr A, Shehata M, Hauser A, Isberg V, Mokrosinski J, Andersen K, et al. The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), Î±-, and Î²-melanocyte stimulating hormone (Î±-MSH, and Î²-MSH), and the conserved core motif HFRW. Neurochem Int. 2017;102:105-113 pubmed publisher
Martineau C, Martin Falstrault L, Brissette L, Moreau R. The atherogenic Scarb1 null mouse model shows a high bone mass phenotype. Am J Physiol Endocrinol Metab. 2014;306:E48-57 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

3492

SKU :

3492/1

product name :

ACTH (1-39)

description :

Potent endogenous MC2 agonist

target :

Melanocortin Receptor Agonists

unit size :

1 mg

category :

Peptides

purity :

95%

storage :

Store at -20°C

observed molecular weight :

4541.1

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

ACTH (1-39) is a potent endogenous melanocortin receptor 2 (MC2) agonist (EC50 = 57 pM). Component of the hypothalamic-pituitary-adrenal (HPA) axis that stimulates glucocorticoid production and release from the adrenal cortex. Induces insulin resistance, promotes a proinflammatory profile and stimulates UCP-1 in adipocytes in vitro .

product keywords :

Potent endogenous MC2R agonists Receptors Melanocortin acethropan Adrenocorticotropic hormone (1-39) Melanocortin Receptors 3492,

extended description :

Potent endogenous MC2 agonist

formula :

C207H308N56O58S

formula text :

C207H308N56O58S

cas num :

12279-41-3

USD :

478

USD 2025 :

493 USD

product details :

Potent endogenous MC2 agonist

alt names :

Adrenocorticotropic hormone (1-39)

more info or order :

Tocris Bioscience product webpage