Prion Protein 106-126 (human) | Tocris Bioscience 3491 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Prion Protein 106-126 (human)

catalog :

3491

quantity :

1 mg

price :

239 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Di Domizio J, Zhang R, Stagg L, Gagea M, Zhuo M, Ladbury J, et al. Binding with nucleic acids or glycosaminoglycans converts soluble protein oligomers to amyloid. J Biol Chem. 2012;287:736-47 pubmed publisher

product information

brand :

Tocris

master code :

3491

SKU :

3491/1

product name :

Prion Protein 106-126 (human)

description :

Prion protein fragment

target :

Neuronal Metabolism Peptides and Compounds

category :

Peptides

unit size :

1 mg

species :

Human

observed molecular weight :

1912.26

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Prion peptide fragment that shares many physiochemical features with PrPSc. Exhibits neurotoxicity caused by amplification of PrPC-associated signaling responses and induces NF- B-mediated apoptosis in the mouse neuroblastoma cell line N2a. Forms -sheet-rich, insoluble, protease-resistant fibrils and is used as a model to study prion diseases in vitro .

catalog number base :

3491

product keywords :

Prion protein fragment PrPSc Antiprion Neuronal Metabolism Prion Protein 3491,

extended description :

Prion protein fragment

formula :

C 80 H 138 N 26 O 24 S 2

formula text :

C80H138N26O24S2

cas num :

148439-49-0

2020 USD :

239

2021 USD :

239 USD

storage :

Desiccate at -20°C

more info or order :

Tocris Bioscience product webpage