This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Tocris Bioscience
product type :
chemical
product name :
Prion Protein 106-126 (human)
catalog :
3491/1
quantity :
1 mg
price :
239 USD
citations: 1
Reference
Di Domizio J, Zhang R, Stagg L, Gagea M, Zhuo M, Ladbury J, et al. Binding with nucleic acids or glycosaminoglycans converts soluble protein oligomers to amyloid. J Biol Chem. 2012;287:736-47 pubmed publisher
product information
brand :
Tocris
SKU :
3491/1
product name :
Prion Protein 106-126 (human)
unit sizes :
1 mg
description :
Prion protein fragment
target :
Neuronal Metabolism Peptides and Compounds
category :
Peptides
species :
Human
storage :
Desiccate at -20°C
observed molecular weight :
1912.26
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
Prion peptide fragment that shares many physiochemical features with PrPSc. Exhibits neurotoxicity caused by amplification of PrPC-associated signaling responses and induces NF- B-mediated apoptosis in the mouse neuroblastoma cell line N2a. Forms -sheet-rich, insoluble, protease-resistant fibrils and is used as a model to study prion diseases in vitro .
catalog number base :
3491
extended description :
Prion protein fragment
formula :
C 80 H 138 N 26 O 24 S 2
formula text :
C80H138N26O24S2
cas num :
148439-49-0
USD :
239 USD
default size :
TRUE
product details :
Prion protein fragment
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK