4-IPP | Tocris Bioscience 3429/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

4-IPP

catalog :

3429/10

quantity :

10 mg (also 50 mg)

price :

203 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Alban T, Bayık D, Otvos B, Rabljenovic A, Leng L, Jia Shiun L, et al. Glioblastoma Myeloid-Derived Suppressor Cell Subsets Express Differential Macrophage Migration Inhibitory Factor Receptor Profiles That Can Be Targeted to Reduce Immune Suppression. Front Immunol. 2020;11:1191 pubmed publisher
Subbannayya T, Leal Rojas P, Barbhuiya M, Raja R, Renuse S, Sathe G, et al. Macrophage migration inhibitory factor - a therapeutic target in gallbladder cancer. BMC Cancer. 2015;15:843 pubmed publisher
Salazar N, MuÃ±oz D, Kallifatidis G, Singh R, JordÃ M, Lokeshwar B. The chemokine receptor CXCR7 interacts with EGFR to promote breast cancer cell proliferation. Mol Cancer. 2014;13:198 pubmed publisher
Takahashi H, Nakayama R, Hayashi S, Nemoto T, Murase Y, Nomura K, et al. Macrophage migration inhibitory factor and stearoyl-CoA desaturase 1: potential prognostic markers for soft tissue sarcomas based on bioinformatics analyses. PLoS ONE. 2013;8:e78250 pubmed publisher

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

3429

SKU :

3429/10

product name :

4-IPP

Description :

Inhibitor of macrophage migration inhibitory factor (MIF); suicide substrate

target :

Cytokine Compounds

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

282.08

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

4-IPP is an inhibitor of macrophage migration inhibitory factor (MIF). Acts as a suicide substrate to inactivate MIF catalytic and biological functions; inhibits MIF-associated liver enzyme activity in vivo . Also inhibits migration and anchorage independence of human lung adenocarcinoma cell lines in vitro .

extended description :

Inhibitor of macrophage migration inhibitory factor (MIF); suicide substrate

chemical name text :

4-Iodo-6-phenylpyrimidine

formula :

C 10 H 7 IN 2

formula text :

C10H7IN2

cas num :

41270-96-6

USD :

203 USD

product details :

Inhibitor of macrophage migration inhibitory factor (MIF); suicide substrate

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage