CP 99994 dihydrochloride | Tocris Bioscience 3417 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CP 99994 dihydrochloride

catalog :

3417

quantity :

10 mg (also 50 mg)

price :

233 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Yin J, Chapman K, Clark L, Shao Z, Borek D, Xu Q, et al. Crystal structure of the human NK1 tachykinin receptor. Proc Natl Acad Sci U S A. 2018;115:13264-13269 pubmed publisher
Horn C, Wang H, Estival L, Meyers K, Magnusson M. Novel dynamic measures of emetic behavior in musk shrews. Auton Neurosci. 2013;179:60-7 pubmed publisher

product information

brand :

Tocris

master code :

3417

SKU :

3417/10

product name :

CP 99994 dihydrochloride

description :

High affinity NK1 antagonist

target :

NK1 Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

369.33

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

High affinity NK1 antagonist (Ki = 0.145 nM in vitro ). Also displays high ex vivo binding potency in gerbil striatum (IC50 = 36.8 nM). Attenuates endothelium-dependent contraction induced by substance P.

catalog number base :

3417

product keywords :

pfizer CP99994 neurokinin 1 receptors nk1 tachykinin substance p antagonists NK1 Receptor 3417, Neurokinin NK1

extended description :

High affinity NK1 antagonist

chemical name text :

(2S,3S)-N-[(2-Methoxyphenyl)methyl]-2-phenyl-3-piperidinamine dihydrochloride

formula :

C 19 H 24 N 2 O.2HCl

formula text :

C19H24N2O.2HCl

cas num :

145148-39-6

2020 USD :

224

2021 USD :

233 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage