COG 133 | Tocris Bioscience 3405 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

COG 133

catalog :

3405

quantity :

1 mg

price :

244 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Tavazoie M, Pollack I, Tanqueco R, Ostendorf B, Reis B, Gonsalves F, et al. LXR/ApoE Activation Restricts Innate Immune Suppression in Cancer. Cell. 2018;172:825-840.e18 pubmed publisher

product information

brand :

Tocris

master code :

3405

SKU :

3405/1

product name :

COG 133

description :

ApoE peptide fragment

target :

LDL Receptor Peptides

category :

Peptides

unit size :

1 mg

observed molecular weight :

2169.73

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Apolipoprotein (ApoE) peptide fragment that functions via the low-density lipoprotein receptor-related protein (LRP). Substantially reduces the symptoms of experimental autoimmune encephalomyelitis, a model of human multiple sclerosis, and suppresses inflammation, demyelination and infiltration of cells into the spinal cord. Also acts as a non-competitive antagonist at 7 nicotinic acetylcholine receptors (IC50 = 445 nM).

catalog number base :

3405

product keywords :

apoE peptide fragment 7 alpha7 a7 nAChR antagonists NMDA Nicotinic Receptors Acetylcholine Glutamate N-Methyl-D-Aspartate iGluR Ionotropic COG133 apoE(133149) LDL lipoprotein apolipoproteins apoE(133-149) Nicotinic (a7) Receptors LDL Receptors 3405,

extended description :

ApoE peptide fragment

formula :

C 97 H 181 N 37 O 19

formula text :

C97H181N37O19

cas num :

514200-66-9

2020 USD :

234

2021 USD :

244 USD

alt names :

apoE(133-149)

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage