EIPA | Tocris Bioscience 3378/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

EIPA

catalog :

3378/10

quantity :

10 mg (also 50 mg)

price :

122 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Neubert P, Homann A, Wendelborn D, Bär A, Krampert L, Trum M, et al. NCX1 represents an ionic Na+ sensing mechanism in macrophages. PLoS Biol. 2020;18:e3000722 pubmed publisher
Knudsen J, Hamilton A, Ramracheya R, Tarasov A, Brereton M, Haythorne E, et al. Dysregulation of Glucagon Secretion by Hyperglycemia-Induced Sodium-Dependent Reduction of ATP Production. Cell Metab. 2019;29:430-442.e4 pubmed publisher

image

image 1 :

Cat.No. 3378 - EIPA C11H18ClN7O CAS No. 1154-25-2

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

3378

SKU :

3378/10

product name :

EIPA

Description :

Inhibits TRPP3-mediated currents; also inhibits the Na+/H+ exchanger (NHE)

target :

TRPP Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

299.76

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

EIPA is a TRPP3 channel inhibitor (IC50 = 10.5 M). Inhibits the Na+/H+ exchanger (NHE). Derivative of amiloride (Cat. No. 0890).

extended description :

Inhibits TRPP3-mediated currents; also inhibits the Na+/H+ exchanger (NHE)

chemical name text :

3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide

formula :

C 11 H 18 ClN 7 O

formula text :

C11H18ClN7O

cas num :

1154-25-2

USD :

122 USD

product details :

Inhibits TRPP3-mediated currents; also inhibits the Na+/H+ exchanger (NHE)

alt names :

Ethylisopropyl amiloride

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage