Valinomycin | Tocris Bioscience 3373/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Valinomycin

catalog :

3373/10

quantity :

10 mg (also 50 mg)

price :

79 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Fessler E, Eckl E, Schmitt S, Mancilla I, Meyer Bender M, Hanf M, et al. A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol. Nature. 2020;579:433-437 pubmed publisher
MacDonald J, Bothun A, Annis S, Sheehan H, Ray S, Gao Y, et al. A nanoscale, multi-parametric flow cytometry-based platform to study mitochondrial heterogeneity and mitochondrial DNA dynamics. Commun Biol. 2019;2:258 pubmed publisher
Yin W, Kim H, Wang S, Gunawan F, Wang L, Kishimoto K, et al. The potassium channel KCNJ13 is essential for smooth muscle cytoskeletal organization during mouse tracheal tubulogenesis. Nat Commun. 2018;9:2815 pubmed publisher
Cassilly C, Maddox M, Cherian P, Bowling J, Hamann M, Lee R, et al. SB-224289 Antagonizes the Antifungal Mechanism of the Marine Depsipeptide Papuamide A. PLoS ONE. 2016;11:e0154932 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

3373

SKU :

3373/10

product name :

Valinomycin

description :

Selective K+ ionophore

target :

Ionophores

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

90%

storage :

Store at -20°C

observed molecular weight :

1111.32

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Valinomycin is a selective K+ ionophore (K0.5 values are 48, 73, 75, 93 and 246 mM for K+, Rb+, Cs+, Na+ and Li+ respectively) that transports K+ across biological and artificial lipid membranes. Inhibits Ca2+-ATPase activity and induces apoptosis through mitochondrial membrane depolarization, caspase-3 activation and phosphatidylserine translocation in vitro .

product keywords :

Selective K+ ionophores Potassium antibiotics Ionophores Antibiotics 3373,

extended description :

Selective K+ ionophore

chemical name text :

Cyclo(D- -hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D- -hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D- -hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl)

formula :

C54H90N6O18

formula text :

C54H90N6O18

cas num :

2001-95-8

USD :

USD 2025 :

79 USD

product details :

Selective K+ ionophore

more info or order :

Tocris Bioscience product webpage