SB 271046 hydrochloride | Tocris Bioscience 3368 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SB 271046 hydrochloride

catalog :

3368

quantity :

10 mg (also 50 mg)

price :

225 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

3368

SKU :

3368/10

product name :

SB 271046 hydrochloride

description :

Selective 5-HT6 antagonist; orally active

target :

5-HT6 Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

488.45

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective, orally active 5-HT6 antagonist (pKi values are 9.02-8.92, 6.55, 6.35, 6.27, 6.05, 5.95, 5.76, 5.73, 5.62, 5.55, 5.41, 5.39, 5.27 and 4.99 at 5-HT6, 5-HT1D, 5-HT1A, D3, 5-HT1B, 5-HT1F, 1B, 5-HT2C, 5-HT2A, D2, 5-HT2B, 5-HT7, 5-HT4 and 5-HT1E respectively) and is 200-fold selective over 55 other receptors, enzymes and ion channels. Increases extracellular glutamate and aspartate in the frontal cortex, and exhibits anticonvulsant activity (EC50 = 0.16 M).

catalog number base :

3368

product keywords :

Orally active selective 5-HT6 antagonists Serotonin Receptors 5-Hydroxytryptamine SB271046 hydrochloride GlaxoSmithKline GSK 5-HT6 Receptors 3368,

extended description :

Selective 5-HT6 antagonist; orally active

chemical name text :

5-Chloro-N-[4-methoxy-3-(1-piperazinyl)phenyl]-3-methyl-benzo[b]thiophen-2-sulfonamide hydrochloride

formula :

C 20 H 22 ClN 3 O 3 S 2 .HCl

formula text :

C20H22ClN3O3S2.HCl

cas num :

209481-24-3

2020 USD :

218

2021 USD :

225 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage